ORIGINAL ARTICLE
Year : 2017 | Volume
: 3 | Issue : 2 | Page : 84--87
Evaluation of antidiabetic property of quail egg on alloxan-induced diabetes mellitus in Wistar albino rats
Amarachi Agbafor1, David Arome2, Wilson Goodness Oluebube1
1 Department of Biochemistry, Michael Okpara University of Agriculture, Umudike, Abia, Nigeria
2 Department of Public Health, School of Public Health, Texila American University, Georgetown, Guyana
Correspondence Address:
David Arome
School of Public Health, Texila American University, Georgetown
Guyana
Background: Alloxan-induced hyperglycemia has been a useful experimental model to study activity of hypoglycemic agents. Alloxan has been utilized in the diabetes model due to its ability to produce a high percentage of the endogenous beta cells destruction.
Objective: The principal objective of the study was to evaluate the antidiabetic property of quail egg on alloxan-induced diabetes in Wistar albino rats.
Materials and Methods: Freshly, prepared quail egg of 0.5, 1.0, and 1.5 ml and reference standard drug of metformin 10 mg/kg were used in the study, administered through oral route. The antidiabetic property of the quail egg was evaluated using alloxan-induced diabetes in Wistar albino model.
Results: The quail egg-treated groups (1.0 and 1.5 ml) exhibited considerable significant (P < 0.05) antidiabetic property with drastic reduction in the blood glucose level. There was a significant reduction in the blood glucose levels in the quail egg-treated groups at day 7 and 14, respectively. The quail egg-treated group of 1.5 ml showed better antidiabetic activity characterized with a significant reduction of blood glucose level compared to the positive group which received the standard reference drug metformin monohydrate 10 mg/kg.
Conclusion: The research findings of the study clearly showed that quail egg possesses an antidiabetic property.
How to cite this article:
Agbafor A, Arome D, Oluebube WG. Evaluation of antidiabetic property of quail egg on alloxan-induced diabetes mellitus in Wistar albino rats.J Curr Res Sci Med 2017;3:84-87
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How to cite this URL:
Agbafor A, Arome D, Oluebube WG. Evaluation of antidiabetic property of quail egg on alloxan-induced diabetes mellitus in Wistar albino rats. J Curr Res Sci Med [serial online] 2017 [cited 2021 Jan 17 ];3:84-87
Available from: https://www.jcrsmed.org/article.asp?issn=2455-3069;year=2017;volume=3;issue=2;spage=84;epage=87;aulast=Agbafor;type=0 |
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