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ORIGINAL ARTICLE
Year : 2020  |  Volume : 6  |  Issue : 2  |  Page : 129-133

Comparison of fine-needle aspiration cytology and histopathological reports of thyroid nodules: An observational study


1 Department of Surgery, Maharashtra Institute of Medical Sciences and Research, Medical College, Latur, Maharashtra, India
2 Department of Physiology, Maharashtra Institute of Medical Sciences and Research, Medical College, Latur, Maharashtra, India
3 Department of Microbiology, Maharashtra Institute of Medical Sciences and Research, Medical College, Latur, Maharashtra, India

Correspondence Address:
Abhijit Satish Rayate
Department of Surgery, Maharashtra Institute of Medical Sciences and Research, Medical College, Latur - 413 512, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcrsm.jcrsm_49_20

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Context: Thyroid nodule refers to a distinct lesion within the gland that is palpably or radiologically distinct from the surrounding thyroid parenchyma. The differential diagnosis of a thyroid nodule is crucial, as malignancy necessitates surgery. Fine-needle aspiration cytology (FNAC) is the recommended initial screening test for the diagnosis of thyroid nodules according to the revised Bethesda system for reporting the thyroid cytopathology system. A well-performed FNAC and reporting by expert pathologist help to avoid unnecessary surgeries in benign nodules where only conservative management or follow-up is needed. Aims: The aim of this study is to study the correlation between FNAC reports and final histopathological reports of specimens of thyroidectomy. Setting and Design: An observational study at a tertiary care hospital. Subjects and Methods: This observational study included 74 patients who were euthyroid and had undergone FNAC, thyroid surgery, and histopathology in the same institution. The results of FNAC and histopathology reports were correlated and tabulated into neoplastic and nonneoplastic categories. Statistical Analysis Used: Descriptive analysis was carried out and presented as percentages. Results: A total of 59 nonneoplastic lesions and 15 neoplastic lesions were found on FNAC. On histopathological examination, there were 60 nonneoplastic and 14 neoplastic lesions. Comparing the results in this study, FNAC showed sensitivity of 100%, specificity of 98.33%, the positive predictive value of 98.33%, and the negative predictive value of 100%. The diagnostic accuracy was 98.65%. Conclusions: FNAC is the most useful, safe, accurate, relatively simple, inexpensive tool to diagnose thyroid pathology and to differentiate between neoplastic and nonneoplastic etiologies.


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